It’s his brother ______ never been to Australia. You’d better take him with you.

that is

who is

that have 　

 who has

句意：就是他的弟弟从没去过澳大利亚。你最好带他和你去。根据句意及题干分析此题是考查强调句型，因为强调的是his brother，是人，所以用who引导是现在完成时态，故选D。

Though ____ the dangers of smoking to their health, smokers still find it hard to give up smoking.

aware of

are aware of

be aware of

考查状语从句的省略：句意：虽然很多经常吸烟的人已经意识到抽烟对他们健康造成了很严重的后果，但是他们仍然发现很难戒烟。Though引导的让步状语从句是省略句，完整的句子是：though smokers are aware of the dangers of smoking to their health。当主从句的主语一致的时候，可以省略从句的主语和be动词，选B

Going on a trip into         space must be quite         exciting experience.

/; the 

/; an

the; the 

the; an

考查冠词。句意：太空旅行是令人兴奋的经历。第一空不填，space前面不加冠词，第二空后面的experience作“经历”时是可数名词，表示“一次令人兴奋的经历"。exciting首字母的发音为元音音素，因此应填an。故选B项。