It was along the Mississippi River _________ Mark Twain spent much of his childhood.

how

which

that

where

此处构成It was...that...强调句式，句中强调了介词短语along the Mississippi River。故选C。

--- I'm afraid I can't complete the marathon next week.

---              ! You have been practicing a lot.

No problem

Go ahead

Cheer up

Good luck

考查交际用语。句意：---恐怕我下周不能完成马拉松比赛。---振作起来！你一直一直在不断练习。A.No problem没问题；B. Go  ahead请干吧；请便吧；C.Cheer up高兴起来；振作起来；D. Good luck祝您好运。由下文可知说话人担心，完不成马拉松比赛，由“你一直不断练习”可推断表示鼓励“振作起来”。故选C项。

Going on a trip into         space must be quite         exciting experience.

/; the 

/; an

the; the 

the; an

考查冠词。句意：太空旅行是令人兴奋的经历。第一空不填，space前面不加冠词，第二空后面的experience作“经历”时是可数名词，表示“一次令人兴奋的经历"。exciting首字母的发音为元音音素，因此应填an。故选B项。

never I have read

never have I read

ever I have read

ever have I read

Only after my friend came ______.

did the computer repair

he repaired the computer

was the computer repaired

the computer was repaired

句意：直到我的朋友来了之后电脑才被修理。放于句首的only修饰时间状语从句after my friend came，主句应进行部分倒装，将助动词was提到主语前面，故选C项。

A study shows the students who are engaged in after-school  activities are happier than        who are not.

ones

those

these

them

考查代词。句意：一项研究表明，参加课外活动的学生比不参加课外活动的学生更开心。空格处代词与the students是对应关系，可以用the ones 或者those替代。“them”指代前面提到的复数名词，不能与the students形成对应关系，“these”一般不用定语从句修饰。故选B项。

All we need          a piece of advice on how we can improve our time management.

are

is

were

was

考查be动词和时态。句意：我们需要的只是一条关于如何改进时间管理的建议。分析句子可知，说明一般情况应该用一般现在时，这句话的主语是All we need, 所以为主语从句，当主语从句作主语时，谓语动词用单数，所以用is。故选B项。